How is oxygen transported to cells?

One of the basic misunderstandings of the 20th and 21st centuries is how oxygen is transported. Cells Cell membranes have always been assumed to be easily penetrable by oxygen without the need for a specific transport mechanism; However, this is not the case. Oxygen has to be supplied through the membrane, like all other nutrients, and fatty acids in the cell membrane are the facilitators. Having free oxygen running around the cell oxidizing things would be a disaster!

​An article that was published in 1976 by the American Academy of Pediatrics says something very interesting and that most of the scientific intelligence omitted ( Campbell, Crozier and Caton, 1976 ).

Impaired oxygen supply and impaired health in cystic fibrosis patients correlate with abnormal changes in the fatty acid composition of lipids in the blood. As the proportion of oleates increases and that of linoleates decreases , the interference of the red cell membrane with the formation of intracellular oxyhemoglobin increases and the arterial pressure of oxygen decreases.The physicochemical basis of these changes seems to be that oleic acid and linoleic acid differ in their ability to undergo reversible oxygenation in response to Changes in Oxygen Pressure The oxygen complex of linoleic acid dissociates at relatively high pressures, whereas that of oleic acid dissociates only at low pressures, therefore, excessive substitution of oleic acid for linoleic acid in the Membrane lipids lower intracellular oxygen pressure to a level where it oxygenates it tion of hemoglobin and any other process that requires oxygen is affected. "

​The last section is deliberately bold; Basically, he says that the more oleic acid (omega-9 found in olive oil) in a cell membrane, the less efficient the transport of oxygen is through the membranes, and the more linoleic acid (omega-6), more efficient is the transport of oxygen is also important, the document states that the oxygen dissociation curve of linoleic acid is similar to hemoglobin, which is what it would take for a cell membrane to extract oxygen from the heme molecule that took him there.

​This elegantly unites the observed results when supplemented with adequate, unadulterated (unprocessed) omega-6 linoleic acid (the results of which are better energy levels, higher endurance, and shorter recovery time).

REFERENCES

Campbell, I., Crozier, D. and Caton, R. (1976). Abnormal fatty acid composition and impaired oxygen supply in patients with cystic fibrosis, American Academy of Pediatrics, 57 (4). Recovered from https: //www.ncbi.nlm.nih. gov / pubmed / 1264543 .



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